Package: ceas 1.0.0

Rachel House

ceas: Cellular Energetics Analysis Software

Analysis and visualization of cellular energetics data from Agilent Seahorse XF96. Cellular energetics is how cells make, use, and distribute units of energy (primarily ATP). Measuring real-time cellular energetics is essential to understanding a tissue or cell’s bioenergetic state and fuel dependencies. The Seahorse machine measures a cell’s or matrix’s oxygen consumption rate (OCR) – a proxy of oxidative phosphorylation – and extracellular acidification rate – a proxy of glycolysis. This package offers flexible and fast analysis and plotting capabilities for such data using the methods described by Mookerjee et al. (2017) <doi:10.1074/jbc.m116.774471>.

Authors:Rachel House [aut, cre], James Eapen [aut], Hui Shen [fnd], Carrie Graveel [fnd], Matthew Steensma [fnd], Van Andel Institute [cph]

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NEWS

Peer review:

Bug tracker:https://github.com/jamespeapen/ceas/issues

On CRAN:

10 exports 1 stars 2.12 score 37 dependencies 3 scripts 578 downloads

Last updated 28 days agofrom:2d48eaddd3. Checks:OK: 7. Indexed: yes.

Exports:atp_plotbioscope_plotget_energeticsget_energetics_summaryget_rate_summarymake_bioscope_plotnormalizepartition_datarate_plotread_data

Dependencies:cellrangerclicolorspacecpp11crayondata.tablefansifarverggplot2gluegtablehmsisobandlabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellnlmepillarpkgconfigprettyunitsprogressR6RColorBrewerreadxlrematchrlangscalestibbleutf8vctrsviridisLitewithr